Reactivity: | Human |
Applications: | FC |
Host Species: | Rabbit |
Isotype: | IgG |
Clonality: | Monoclonal Antibody |
Conjugation: | ABflo® 488. Ex:491nm. Em:516nm. |
Gene Name: | interferon gamma receptor 1 |
Gene Symbol: | IFNGR1 |
Synonyms: | CD119; IFNGR; IMD27A; IMD27B |
Gene ID: | 3459 |
UniProt ID: | P15260 |
Clone ID: | 0G7G6 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 18-245 of human CD119/IFNGR1. (NP_000407.1). |
Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
Purification Method: | Affinity purification |
Concentration: | 0.04 mg/mL |
Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
Documents: | Manual-IFNGR1 Antibody |
Background
This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.
Images
![]() | Flow cytometry: 1×10^6 HepG2 cells were surface-stained with ABflo® 488 Rabbit anti-Human CD119/IFNGR1 mAb(A23816,5 μl/Test,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,blue line).Non-fluorescently stained HepG2 cells were used as blank control (red line). |
![]() | Flow cytometry: 1×10^6 CHO cells(negative control) were surface-stained with ABflo® 488 Rabbit anti-Human CD119/IFNGR1 mAb(A23816,5 μl/Test,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,blue line).Non-fluorescently stained CHO cells were used as blank control (red line). |
![]() | Flow cytometry:1×10^6 HepG2 cells were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or ABflo® 488 Rabbit anti-Human CD119/IFNGR1 mAb(A23816,5 μl/Test,right). |
![]() | Flow cytometry: 1×10^6 Human PBMC were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or ABflo® 488 Rabbit anti-Human CD119/IFNGR1 mAb (A23816,5 μl/Test,right). |
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