Your shopping cart is empty!
ABflo® 488 Rabbit anti-Human CD171/L1CAM mAb (100 T)
| Reactivity: | Human |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 488. Ex:491nm. Em:516nm. |
| Gene Name: | L1cell adhesion molecule |
| Gene Symbol: | L1CAM |
| Synonyms: | S10; HSAS; HYCX; MASA; MIC5; SPG1; CAML1; CD171; HSAS1; N-CAML1; NCAM-L1; N-CAM-L1 |
| Gene ID: | 3897 |
| UniProt ID: | P32004 |
| Clone ID: | 4T7I8 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-1120 of human CD171/L1CAM (NP_000416.1). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-L1CAM Antibody |
Background
The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons.
Images
 | Flow cytometry:1×10^6 Jurkat cells (negative control,Left) and MCF7 cells (Right) were surface-stained with ABflo® 488 Rabbit anti-Human CD171/L1CAM mAb(A22590,5 μl/Test,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
You may also be interested in:
Related Products
-10%
-16%
