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ABflo® 488 Rabbit anti-Human CD270/HVEM mAb (100 T)
| Reactivity: | Human |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 488. Ex:491nm. Em:516nm. |
| Gene Name: | TNF receptor superfamily member 14 |
| Gene Symbol: | TNFRSF14 |
| Synonyms: | TR2; ATAR; HVEA; HVEM; CD270; LIGHTR |
| Gene ID: | 8764 |
| UniProt ID: | Q92956 |
| Clone ID: | 2L8P6 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 39-162 of human CD270/HVEM(NP_003811.2) |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-TNFRSF14 Antibody |
Background
This gene encodes a member of the TNF (tumor necrosis factor) receptor superfamily. The encoded protein functions in signal transduction pathways that activate inflammatory and inhibitory T-cell immune response. It binds herpes simplex virus (HSV) viral envelope glycoprotein D (gD), mediating its entry into cells. Alternative splicing results in multiple transcript variants.
Images
 | Flow cytometry:1×10^6 HAP1 cells (negative control,left) and HEL cells (right) were surface-stained with ABflo® 488 Rabbit anti-Human CD270/HVEM mAb(A24417,5 μl/Test,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry:1×10^6 HEL cells were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or ABflo® 488 Rabbit anti-Human CD270/HVEM mAb(A24417,5 μl/Test,right). |
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