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ABflo® 488 Rabbit anti-Human CD271/NGFR mAb (100 T)
| Reactivity: | Human |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 488. Ex:491nm. Em:516nm. |
| Gene Name: | nerve growth factor receptor |
| Gene Symbol: | NGFR |
| Synonyms: | CD271; p75NTR; TNFRSF16; p75(NTR); Gp80-LNGFR |
| Gene ID: | 4804 |
| UniProt ID: | P08138 |
| Clone ID: | 9N3J3 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 29-250 of human CD271/NGFR (NP_002498.1). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-NGFR Antibody |
Background
Nerve growth factor receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain.
Images
 | Flow cytometry:1×10^6 K-562 cells (negative control,Left) and SK-N-MC cells (Right) were surface-stained with ABflo® 488 Rabbit anti-Human NGFR/CD271 mAb(A23118,5 μl/Test,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry:1×10^6 SK-N-MC cells were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or ABflo® 488 Rabbit anti-Human NGFR/CD271 mAb(A23118,5 μl/Test,right). |
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