Your shopping cart is empty!
ABflo® 488 Rabbit anti-Human CD51 mAb (100 T)
| Reactivity: | Human |
| Applications: | FC (intra) |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 488. Ex:491nm. Em:516nm. |
| Gene Name: | integrin subunit alpha V |
| Gene Symbol: | ITGAV |
| Synonyms: | CD51; MSK8; VNRA; VTNR |
| Gene ID: | 3685 |
| UniProt ID: | P06756 |
| Clone ID: | 5M6Y2 |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 949-1048 of human CD51 (NP_002201.2). |
| Dilution: | FC (intra),5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-ITGAV Antibody |
Background
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.
Images
 | Flow cytometry:1×10^6 MOLT-4 cells (Low Expression,left) and BeWo cells (right) were intracellularly-stained with ABflo® 488 Rabbit anti-Human CD51 mAb(A22298,5 μl/Test,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry:1×10^6 BeWo cells were intracellularly-stained with ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or ABflo® 488 Rabbit anti-Human CD51 mAb(A22298,5 μl/Test,right). |
You may also be interested in:
