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ABflo® 488 Rabbit anti-Human GATA3 mAb (100 T)
| Reactivity: | Human |
| Applications: | FC (intra) |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 488. Ex:491nm. Em:516nm. |
| Gene Name: | GATA binding protein 3 |
| Gene Symbol: | GATA3 |
| Synonyms: | HDR; HDRS |
| Gene ID: | 2625 |
| UniProt ID: | P23771 |
| Clone ID: | 8P1R2 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human GATA3 (NP_001002295.1). |
| Dilution: | FC (intra),5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.01 mg/ml |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-GATA3 Antibody |
Background
This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia.
Images
 | Flow cytometry: 1×10^6 Raji cells (negative control,left) and MCF7 cells (right) were intracellularly-stained with ABflo® 488 Rabbit anti-Human GATA3 mAb (A25945,5 μl/Test,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry: 1×10^6 MCF7 cells were intracellularly-stained with ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or ABflo® 488 Rabbit anti-Human GATA3 mAb (A25945,5 μl/Test,right). |
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