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ABflo® 488 Rabbit anti-Human IgE mAb (100 T)
| Reactivity: | Human |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 488. Ex:491nm. Em:516nm. |
| Gene Name: | immunoglobulin heavy constant epsilon |
| Gene Symbol: | IGHE |
| Synonyms: | IgE |
| Gene ID: | 3497 |
| UniProt ID: | P01854 |
| Clone ID: | 7H4F9 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 104-428 of human IgE (P01854). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-IGHE Antibody |
Background
IgE is the class of antibodies produced in the lungs, skin, and mucous membranes. It may protect against parasite invasion, but it is a major factor in allergic reactions. The antigen-specific IgE interacts with mast cells and eosinophils, triggers the release of histamine, leukotrienes and other substances that lead to the itching, sneezing and congestion of allergies - and the life threatening respiratory distress of asthma and anaphylactic shock.
Images
 | Flow cytometry:1×10^6 HeLa cells(negative control,left) and Human PBMC(right) were surface-stained with ABflo® 488 Rabbit anti-Human IgE mAb(A23696,5 μl/Test,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
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