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ABflo® 488 Rabbit anti-Human TROP-2 mAb (100 T)
| Reactivity: | Human |
| Applications: | IF/ICC, FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 488. Ex:491nm. Em:516nm. |
| Gene Name: | tumor associated calcium signal transducer 2 |
| Gene Symbol: | TACSTD2 |
| Synonyms: | EGP1; GP50; M1S1; EGP-1; TROP2; GA7331; GA733-1 |
| Gene ID: | 4070 |
| UniProt ID: | P09758 |
| Clone ID: | 7H0A2 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 27-274 of human TROP-2 (NP_002344.2). |
| Dilution: | IF/ICC,1:50 - 1:100|FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-TACSTD2 Antibody |
Background
This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.
Images
 | Immunofluorescence analysis of MCF7 cells using ABflo® 488 Rabbit anti-Human TROP-2 mAb (A22577) at dilution of 1:20 (40x lens). Blue: DAPI for nuclear staining. |
 | Confocal imaging of A-431 cells using ABflo® 488 Rabbit anti-Human TROP-2 mAb (A22577, dilution 1:100).DAPI was used for nuclear staining (Blue). Objective: 100x. |
 | Flow cytometry:1×10^6 U-118MG cells (negative control,left) and MCF7 cells (right) were surface-stained with ABflo® 488 Rabbit anti-Human TROP-2 mAb(A22577,5 μl/Test,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
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