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ABflo® 488 Rabbit anti-Human VCAM-1/CD106 mAb (100 T)
| Reactivity: | Human |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 488. Ex:491nm. Em:516nm. |
| Gene Name: | Vascular cell adhesion molecule 1 |
| Gene Symbol: | VCAM1 |
| Synonyms: | CD106; INCAM-100 |
| Gene ID: | 7412 |
| UniProt ID: | P19320 |
| Clone ID: | 1X9Q9 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-698 of human VCAM1 (NP_001069.1). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-VCAM1 Antibody |
Background
This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene.
Images
 | Flow cytometry:1×10^6 293T cells(negative control,left) and 293T(Transfection,right) cells were surface-stained with ABflo® 488 Rabbit anti-Human VCAM-1/CD106 mAb(A23397,5 μl/Test,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,blue line).Non-fluorescently stained cells was used as blank control (red line). |
 | Flow cytometry:1×10^6 293T(Transfection) cells were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or ABflo® 488 Rabbit anti-Human VCAM-1/CD106 mAb(A23397,5 μl/Test,right). |
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