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ABflo® 488 Rabbit anti-Mouse CD146 mAb (100 T)
| Reactivity: | Mouse |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 488. Ex:491nm. Em:516nm. |
| Gene Name: | melanoma cell adhesion molecule |
| Gene Symbol: | Mcam |
| Synonyms: | CD146; CD149; Muc18; s-endo; 1-gicerin; s-gicerin |
| Gene ID: | 84004 |
| UniProt ID: | Q8R2Y2 |
| Clone ID: | 9B4P9 |
| Immunogen: | Recombinant Protein corresponding to a sequence within amino acids 24-563 of mouse CD146 (NP_075548.2) |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.01 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-Mcam antibody |
Background
Predicted to be involved in angiogenesis and positive regulation of cell migration. Predicted to act upstream of or within heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules. Predicted to be located in external side of plasma membrane; extracellular space; and nucleus. Predicted to be active in plasma membrane. Is expressed in several structures, including adipose tissue; genitourinary system; gut; nervous system; and respiratory system. Orthologous to human MCAM (melanoma cell adhesion molecule).
Images
 | Flow cytometry:1×10^6 CTLL-2 cells (negative control,Left) and bEnd.3 cells (Right) were surface-stained with ABflo® 488 Rabbit anti-Mouse CD146 mAb(A24397,5 μl/Test,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry:1×10^6 bEnd.3 cells were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or ABflo® 488 Rabbit anti-Mouse CD146 mAb(A24397,5 μl/Test,right). |
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