ABflo® 488 Rabbit anti-Mouse CD226/DNAM-1 mAb (100 T)

Brand: Abclonal
Cat. #: A25862
Availability: In Stock

$78.00

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Description

Reactivity:	Mouse
Applications:	FC
Host Species:	Rabbit
Isotype:	IgG
Clonality:	Monoclonal Antibody
Conjugation:	ABflo® 488. Ex:491nm. Em:516nm.
Gene Name:	CD226 antigen
Gene Symbol:	Cd226
Synonyms:	Pta1; DNAM1; DNAM-1; TLiSA1
Gene ID:	225825
UniProt ID:	Q8K4F0
Clone ID:	4D5R2
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 19-254 of mouse CD226/DNAM-1 (NP_848802.2).
Dilution:	FC,5 μl per 10^6 cells in 100 μl volume
Purification Method:	Affinity purification
Concentration:	0.04 mg/mL
Buffer:	PBS with 0.03% proclin300,0.2% BSA, pH7.3.
Storage:	Store at -20°C. Avoid freeze / thaw cycles.
Documents:	Manual-Cd226 antibody

Background

Predicted to enable integrin binding activity and protein kinase binding activity. Acts upstream of or within positive regulation of interferon-gamma production and positive regulation of natural killer cell cytokine production. Located in external side of plasma membrane. Is expressed in embryo. Orthologous to human CD226 (CD226 molecule).

Images

	Flow cytometry: 1×10^6 293T cells (negative control,left) and 293T (Transfection,right) cells were surface-stained with ABflo® 488 Rabbit anti-Mouse CD226/DNAM-1 mAb (A25862,5 μl/Test,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line).
	Flow cytometry: 1×10^6 293T (Transfection) cells were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or ABflo® 488 Rabbit anti-Mouse CD226/DNAM-1 mAb (A25862,5 μl/Test,right).
	Flow cytometry:1×10^6 C57BL/6 Splenocytes cells were surface-stained with ABflo® 647 Rabbit anti-Mouse CD8a mAb (A23904,5 μl/Test) and ABflo® 488 Rabbit anti-Mouse CD226/DNAM-1 mAb (A25862,5 μl/Test,left) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,right).