ABflo® 488 Rabbit anti-Mouse CD56/NCAM mAb (100 T)

Brand: Abclonal
Cat. #: A23369
Availability: In Stock

$290.00

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Description

Reactivity:	Mouse
Applications:	FC
Host Species:	Rabbit
Isotype:	IgG
Clonality:	Monoclonal Antibody
Conjugation:	ABflo® 488. Ex:491nm. Em:516nm.
Gene Name:	neural cell adhesion molecule 1
Gene Symbol:	Ncam1
Synonyms:	CD56; Ncam; E-NCAM; NCAM-1
Gene ID:	17967
UniProt ID:	P13595
Clone ID:	1M8D4
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 20-711 of mouse CD56 (NP_001106675.1).
Dilution:	FC,5 μl per 10^6 cells in 100 μl volume
Purification Method:	Affinity purification
Concentration:	0.04 mg/mL
Buffer:	PBS with 0.03% proclin300,0.2% BSA, pH7.3.
Storage:	Store at -20°C. Avoid freeze / thaw cycles.
Documents:	Manual-Ncam1 antibody

Background

Predicted to enable LRR domain binding activity and phosphatase binding activity. Involved in commissural neuron axon guidance and regulation of semaphorin-plexin signaling pathway. Acts upstream of or within several processes, including homotypic cell-cell adhesion; positive regulation of calcium-mediated signaling; and regulation of exocyst assembly. Located in several cellular components, including external side of plasma membrane; growth cone; and neuronal cell body. Is expressed in several structures, including embryo mesenchyme; nervous system; sensory organ; skin; and urinary system. Human ortholog(s) of this gene implicated in bipolar disorder; middle cerebral artery infarction; and pancreatic cancer. Orthologous to human NCAM1 (neural cell adhesion molecule 1).

Images

	Flow cytometry:1×10^6 L-929 cells(negative control,left) and Neuro-2a cells (right) were surface-stained with ABflo® 488 Rabbit anti-Mouse CD56/NCAM mAb(A23369,5 μl/Test,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,blue line).Non-fluorescently stained cells was used as blank control (red line).
	Flow cytometry:1×10^6 Neuro-2a cells were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or ABflo® 488 Rabbit anti-Mouse CD56/NCAM mAb(A23369,5 μl/Test,right).