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ABflo® 488 Rabbit anti-Mouse FOXP3 mAb (100 T)
| Reactivity: | Mouse |
| Applications: | FC (intra) |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 488. Ex:491nm. Em:516nm. |
| Gene Name: | forkhead box P3 |
| Gene Symbol: | Foxp3 |
| Synonyms: | sf; JM2; scurfin |
| Gene ID: | 20371 |
| UniProt ID: | Q99JB6 |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of mouse Foxp3 (NP_473380.1). |
| Dilution: | FC (intra),5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/ml |
| Buffer: | PBS with 0.09% Sodium azide,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-Foxp3 antibody |
Background
The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene result in the scurfy phenotype (sf). Alternative splicing results in multiple transcript variants.
Images
 | Flow cytometry:1×10^6 C57BL/6 mouse splenocytes were surface-stained with ABflo® 647 Rabbit anti-Mouse CD4 mAb (A24721,5 μl/Test) and then intracellularly-stained with ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or ABflo® 488 Rabbit anti-Mouse FOXP3 mAb (A26228,5 μl/Test,right). |
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