ABflo® 488 Rabbit anti-Mouse JAM-1/CD321 mAb (100 T)

Brand: Abclonal
Cat. #: A25209
Availability: In Stock

$218.00

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Description

Reactivity:	Mouse
Applications:	FC
Host Species:	Rabbit
Isotype:	IgG
Clonality:	Monoclonal Antibody
Conjugation:	ABflo® 488. Ex:491nm. Em:516nm.
Gene Name:	F11 receptor
Gene Symbol:	F11r
Synonyms:	JAM; Jcam; JAM-1; JAM-A; Jcam1; Ly106; ESTM33; 9130004G24
Gene ID:	16456
UniProt ID:	O88792
Clone ID:	5W3W10
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 27-242 of mouse JAM-1/CD321 (NP_766235.1).
Dilution:	FC,5 μl per 10^6 cells in 100 μl volume
Purification Method:	Affinity purification
Concentration:	0.04 mg/mL
Buffer:	PBS with 0.03% proclin300,0.2% BSA, pH7.3.
Storage:	Store at -20°C. Avoid freeze / thaw cycles.
Documents:	Manual-F11r antibody

Background

Predicted to enable PDZ domain binding activity; integrin binding activity; and protein homodimerization activity. Involved in intestinal absorption; regulation of cytokine production; and regulation of membrane permeability. Acts upstream of or within cell adhesion and epithelial cell differentiation. Located in bicellular tight junction. Is expressed in several structures, including 4-8 cell stage embryo; alimentary system; respiratory system; sensory organ; and urinary system. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human F11R (F11 receptor).

Images

	Flow cytometry: 1×10^6 Neuro-2a cells (negative control,left) and bEnd.3 cells (right) were surface-stained with ABflo® 488 Rabbit anti-Mouse JAM-1/CD321 mAb (A25209,5 μl/Test,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line).
	Flow cytometry: 1×10^6 bEnd.3 cells were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or ABflo® 488 Rabbit anti-Mouse JAM-1/CD321 mAb (A25209,5 μl/Test,right).