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ABflo® 594 Rabbit anti-Human CD225/IFITM1 mAb (100 T)
| Reactivity: | Human |
| Applications: | FC (intra) |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 594. Ex:588nm. Em:604nm. |
| Gene Name: | interferon induced transmembrane protein 1 |
| Gene Symbol: | IFITM1 |
| Synonyms: | 9-27; CD225; IFI17; LEU13; DSPA2a |
| Gene ID: | 8519 |
| UniProt ID: | P13164 |
| Clone ID: | 5E4Q2 |
| Immunogen: | Recombinant fusion protein containing a sequence within amino acids 1-80 of human CD225/IFITM1 (NP_003632.4). |
| Dilution: | FC (intra),5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.02 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-IFITM1 Antibody |
Background
Interferon-induced transmembrane (IFITM) proteins are a family of interferon induced antiviral proteins. The family contains five members, including IFITM1, IFITM2 and IFITM3 that belong to the CD225 superfamily. The protein encoded by this gene restricts cellular entry by diverse viral pathogens, such as influenza A virus, Ebola virus and Sars-CoV-2.
Images
 | Flow cytometry:1×10^6 U-251MG cells (Low Expression,left) and K-562 cells (right) were intracellularly-stained with ABflo® 594 Rabbit anti-Human CD225/IFITM1 mAb(A24591,5 μl/Test,orange line) or ABflo® 594 Rabbit IgG isotype control (A23821,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry:1×10^6 K-562 cells were intracellularly-stained with ABflo® 594 Rabbit IgG isotype control (A23821,5 μl/Test,left) or ABflo® 594 Rabbit anti-Human CD225/IFITM1 mAb(A24591,5 μl/Test,right). |
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