ABflo® 594 Rabbit anti-Human CD86 mAb (100 T)

Background

This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.

Images

	Flow cytometry: 1×10^6 K-562 cells (negative control,left) and Raji cells (right) were surface-stained with ABflo® 594 Rabbit anti-Human CD86 mAb(A24256,5 μl/Test,orange line) or ABflo® 594 Rabbit IgG isotype control (A23821,5 μl/Test,blue line).Non-fluorescently stained cells were used as blank control (red line).
	Flow cytometry:1×10^6 Raji cells were surface-stained with ABflo® 594 Rabbit IgG isotype control (A23821,5 μl/Test,left) or ABflo® 594 Rabbit anti-Human CD86 mAb(A24256,5 μl/Test,right).

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