Reactivity: | Human |
Applications: | FC |
Host Species: | Rabbit |
Isotype: | IgG |
Clonality: | Monoclonal Antibody |
Conjugation: | ABflo® 594. Ex:588nm. Em:604nm. |
Gene Name: | CD93 molecule |
Gene Symbol: | CD93 |
Synonyms: | C1QR1; C1qRP; CDw93; ECSM3; MXRA4; C1qR(P); dJ737E23.1 |
Gene ID: | 22918 |
UniProt ID: | Q9NPY3 |
Clone ID: | 3J4J0 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-580 of human CD93 (NP_036204.2). |
Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
Purification Method: | Affinity purification |
Concentration: | 0.04 mg/mL |
Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
Documents: | Manual-CD93 antibody |
Background
The protein encoded by this gene is a cell-surface glycoprotein and type I membrane protein that was originally identified as a myeloid cell-specific marker. The encoded protein was once thought to be a receptor for C1q, but now is thought to instead be involved in intercellular adhesion and in the clearance of apoptotic cells. The intracellular cytoplasmic tail of this protein has been found to interact with moesin, a protein known to play a role in linking transmembrane proteins to the cytoskeleton and in the remodelling of the cytoskeleton.
Images
![]() | Flow cytometry:1×10^6 Jurkat cells (negative control,left) and U-937 cells (right) were surface-stained with ABflo® 594 Rabbit anti-Human CD93 mAb(A24593,5 μl/Test,orange line) or ABflo® 594 Rabbit IgG isotype control (A23821,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
![]() | Flow cytometry:1×10^6 U-937 cells were surface-stained with ABflo® 594 Rabbit IgG isotype control (A23821,5 μl/Test,left) or ABflo® 594 Rabbit anti-Human CD93 mAb(A24593,5 μl/Test,right). |
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