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ABflo® 594 Rabbit anti-Human Galectin 3 mAb (100 T)
| Reactivity: | Human |
| Applications: | FC (intra) |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 594. Ex:588nm. Em:604nm. |
| Gene Name: | galectin 3 |
| Gene Symbol: | LGALS3 |
| Synonyms: | L31; GAL3; MAC2; CBP35; GALBP; GALIG; LGALS2 |
| Gene ID: | 3958 |
| UniProt ID: | P17931 |
| Clone ID: | 9V4L4 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human Galectin 3 (NP_002297.2). |
| Dilution: | FC (intra),5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-LGALS3 Antibody |
Background
This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.
Images
 | Flow cytometry: 1×10^6 Jurkat cells (Low Expression,left) and MCF7 cells (right) were intracellularly-stained with ABflo® 594 Rabbit anti-Human Galectin 3 mAb (A25187,5 μl/Test,orange line) or ABflo® 594 Rabbit IgG isotype control (A23821,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry: 1×10^6 MCF7 cells were intracellularly-stained with ABflo® 594 Rabbit IgG isotype control (A23821,5 μl/Test,left) or ABflo® 594 Rabbit anti-Human Galectin 3 mAb (A25187,5 μl/Test,right). |
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