Reactivity: | Human |
Applications: | FC |
Host Species: | Rabbit |
Isotype: | IgG |
Clonality: | Monoclonal Antibody |
Conjugation: | ABflo® 594. Ex:588nm. Em:604nm. |
Gene Name: | intercellular adhesion molecule 2 |
Gene Symbol: | ICAM2 |
Synonyms: | CD102 |
Gene ID: | 3384 |
UniProt ID: | P13598 |
Clone ID: | 1H1R9 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-223 of human ICAM2/CD102 (NP_000864.2). |
Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
Purification Method: | Affinity purification |
Concentration: | 0.01 mg/mL |
Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
Documents: | Manual-ICAM2 Antibody |
Background
The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene.
Images
![]() | Flow cytometry:1×10^6 293T cells (negative control,left) and Jurkat cells (right) were surface-stained with ABflo® 594 Rabbit anti-Human ICAM2/CD102 mAb(A24588,5 μl/Test,orange line) or ABflo® 594 Rabbit IgG isotype control (A23821,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
![]() | Flow cytometry:1×10^6 Jurkat cells were surface-stained with ABflo® 594 Rabbit IgG isotype control (A23821,5 μl/Test,left) or ABflo® 594 Rabbit anti-Human ICAM2/CD102 mAb(A24588,5 μl/Test,right). |
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