Reactivity: | Human |
Applications: | FC |
Host Species: | Rabbit |
Isotype: | IgG |
Clonality: | Monoclonal Antibody |
Conjugation: | ABflo® 594. Ex:588nm. Em:604nm. |
Gene Name: | triggering receptor expressed on myeloid cells 1 |
Gene Symbol: | TREM1 |
Synonyms: | CD354; TREM-1 |
Gene ID: | 54210 |
UniProt ID: | Q9NP99 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-200 of human TREM1 (NP_061113.1). |
Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
Purification Method: | Affinity purification |
Concentration: | 0.04 mg/ml |
Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
Documents: | Manual-TREM1 antibody |
Background
This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Images
![]() | Flow cytometry: 1×10^6 293T cells (negative control,left) and 293T (Transfection,right) cells were surface-stained with ABflo® 594 Rabbit anti-Human TREM1 mAb (A26874,5 μl/Test,orange line) or ABflo® 594 Rabbit IgG isotype control (A23821,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
![]() | Flow cytometry: 1×10^6 Human PBMC were surface-stained with ABflo® 594 Rabbit IgG isotype control (A23821,5 μl/Test,left) or ABflo® 594 Rabbit anti-Human TREM1 mAb (A26874,5 μl/Test,right). Cells in the monocyte gate were used for analysis. |
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