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ABflo® 610 Rabbit anti-Human CD26/DPP4 mAb (100 T)
| Reactivity: | Human |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 610. Ex:421nm. Em:612nm. |
| Gene Name: | dipeptidyl peptidase 4 |
| Gene Symbol: | DPP4 |
| Synonyms: | CD26; ADABP; ADCP2; DPPIV; TP103 |
| Gene ID: | 1803 |
| UniProt ID: | P27487 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 29-766 of human CD26/DPP4 (NP_001926.2). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/ml |
| Buffer: | PBS with 0.09% Sodium azide,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-DPP4 Antibody |
Background
The DPP4 gene encodes dipeptidyl peptidase 4, which is identical to adenosine deaminase complexing protein-2, and to the T-cell activation antigen CD26. It is an intrinsic type II transmembrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. Dipeptidyl peptidase 4 is highly involved in glucose and insulin metabolism, as well as in immune regulation. This protein was shown to be a functional receptor for Middle East respiratory syndrome coronavirus (MERS-CoV), and protein modeling suggests that it may play a similar role with SARS-CoV-2, the virus responsible for COVID-19.
Images
 | Flow cytometry: 1×10^6 K-562 cells (negative control,left) and NCI-H2452 [H2452] cells (right) were surface-stained with ABflo® 610 Rabbit anti-Human CD26/DPP4 mAb (A26908,5 μl/Test,orange line) or ABflo® 610 Rabbit IgG isotype control (A25826,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry: 1×10^6 Human PBMC cells were surface-stained with ABflo® 610 Rabbit anti-Human CD26/DPP4 mAb (A26908,5 μl/Test,orange line) or ABflo® 610 Rabbit IgG isotype control (A25826,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). Cells in the Lymphocytes gate were used for analysis. |
 | Flow cytometry: 1×10^6 NCI-H2452 [H2452] cells were surface-stained with ABflo® 610 Rabbit IgG isotype control (A25826,5 μl/Test,left) or ABflo® 610 Rabbit anti-Human CD26/DPP4 mAb (A26908,5 μl/Test,right). |
 | Flow cytometry: 1×10^6 Human PBMC cells were surface-stained with ABflo® 610 Rabbit IgG isotype control (A25826,5 μl/Test,left) or ABflo® 610 Rabbit anti-Human CD26/DPP4 mAb (A26908,5 μl/Test,right). Cells in the Lymphocytes gate were used for analysis. |
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