Your shopping cart is empty!
ABflo® 610 Rabbit anti-Human EGFR mAb (100 T)
| Reactivity: | Human |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 610. Ex:421nm. Em:612nm. |
| Gene Name: | Epidermal growth factor receptor |
| Gene Symbol: | EGFR |
| Synonyms: | ERBB; ERRP; HER1; mENA; ERBB1; NNCIS; PIG61; NISBD2 |
| Gene ID: | 1956 |
| UniProt ID: | P00533 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 335-525 of human EGFR (NP_005219.2). |
| Dilution: | FC, 5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/ml |
| Buffer: | PBS with 0.09% Sodium azide,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-EGFR Antibody |
Background
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor, thus inducing receptor dimerization and tyrosine autophosphorylation leading to cell proliferation. Mutations in this gene are associated with lung cancer. EGFR is a component of the cytokine storm which contributes to a severe form of Coronavirus Disease 2019 (COVID-19) resulting from infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2).
Images
 | Flow cytometry: 1×10^6 Jurkat cells (negative control,left) and A-431 cells (right) were surface-stained with ABflo® 610 Rabbit anti-Human EGFR mAb (A26809,5 μl/Test,orange line) or ABflo® 610 Rabbit IgG isotype control (A25826,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry: 1×10^6 A-431 cells were surface-stained with ABflo® 610 Rabbit IgG isotype control (A25826,5 μl/Test,left) or ABflo® 610 Rabbit anti-Human EGFR mAb (A26809,5 μl/Test,right). |
You may also be interested in:
Related Products
-10%
-16%
