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| Reactivity: | Human |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 647. Ex:648nm. Em:664nm. |
| Gene Name: | programmed cell death 1 ligand 2 |
| Gene Symbol: | PDCD1LG2 |
| Synonyms: | B7DC; Btdc; PDL2; CD273; PD-L2; PDCD1L2; bA574F11.2 |
| Gene ID: | 80380 |
| UniProt ID: | Q9BQ51 |
| Clone ID: | 0K9D4 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-219 of human CD273/PD-L2 (NP_079515.2). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.01 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-PDCD1LG2 antibody |
Background
Involved in negative regulation of activated T cell proliferation; negative regulation of interferon-gamma production; and negative regulation of interleukin-10 production. Predicted to be located in plasma membrane. Predicted to be active in external side of plasma membrane. Biomarker of pulmonary tuberculosis.
Images
![]() | Flow cytometry: 1×10^6 Jurkat cells (negative control,left) and KARPAS 299 cells (right) were surface-stained with ABflo® 647 Rabbit anti-Human CD273/PD-L2 mAb (A25274,5 μl/Test,orange line) or ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
![]() | Flow cytometry: 1×10^6 KARPAS 299 cells were surface-stained with ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,left) or ABflo® 647 Rabbit anti-Human CD273/PD-L2 mAb (A25274,5 μl/Test,right). |
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