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ABflo® 647 Rabbit anti-Human CD31/PECAM1 mAb (100 T)
| Reactivity: | Human |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 647. Ex:648nm. Em:664nm. |
| Gene Name: | platelet and endothelial cell adhesion molecule 1 |
| Gene Symbol: | PECAM1 |
| Synonyms: | CD31; PECA1; GPIIA'; PECAM-1; endoCAM; CD31/EndoCAM |
| Gene ID: | 5175 |
| UniProt ID: | P16284 |
| Clone ID: | 4K3S1 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 28-601 of human CD31 (NP_000433.4). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.01 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-PECAM1 Antibody |
Background
The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation.
Images
 | Flow cytometry:1×10^6 SK-BR-3 cells (negative control,left) and HEL cells (right) were surface-stained with ABflo® 647 Rabbit anti-Human CD31/PECAM1 mAb(A22509,5 μl/Test,orange line) or ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry:1×10^6 HEL cells were surface-stained with ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,left) or ABflo® 647 Rabbit anti-Human CD31 mAb(A22509,5 μl/Test,right). |
 | Flow cytometry: 1×10^6 Human PBMC were surface-stained with PE Rabbit anti-Human CD3 mAb (A27110,5 μl/Test) and ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,left) or ABflo® 647 Rabbit anti-Human CD31/PECAM1 mAb (A22509,5 μl/Test,right). Cells in the Lymphocytes gate were used for analysis. |
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