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ABflo® 647 Rabbit anti-Human CEACAM5/CD66e mAb (100 T)
| Reactivity: | Human |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 647. Ex:648nm. Em:664nm. |
| Gene Name: | CEA cell adhesion molecule 5 |
| Gene Symbol: | CEACAM5 |
| Synonyms: | CEA; CD66e |
| Gene ID: | 1048 |
| UniProt ID: | P06731 |
| Clone ID: | 5K8L5 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 35-685 of human CEACAM5/CD66e(NP_004354.3) |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-CEACAM5 Antibody |
Background
This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants.
Images
 | Flow cytometry:1×10^6 293T cells (negative control,Left) and HT-29 cells (Right) were surface-stained with ABflo® 647 Rabbit anti-Human CEACAM5/CD66e mAb(A23022,5 μl/Test,orange line) or ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,blue line). Non-fluorescently stained cells was used as blank control (red line). |
 | Flow cytometry:1×10^6 HT-29 cells were surface-stained with ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,left) or ABflo® 647 Rabbit anti-Human CEACAM5/CD66e mAb(A23022,5 μl/Test,right). |
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