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ABflo® 647 Rabbit anti-Human MMP9 mAb (100 T)
| Reactivity: | Human |
| Applications: | FC (intra) |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 647. Ex:648nm. Em:664nm. |
| Gene Name: | matrix metallopeptidase 9 |
| Gene Symbol: | MMP9 |
| Synonyms: | GELB; CLG4B; MMP-9; MANDP2 |
| Gene ID: | 4318 |
| UniProt ID: | P14780 |
| Clone ID: | 4N4I9 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-707 of human MMP9 (NP_004985.2). |
| Dilution: | FC (intra),5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-MMP9 Antibody |
Background
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling.
Images
 | Flow cytometry: 1×10^6 293T cells(Low Expression,left) and 293T(Transfection,right) cells were intracellularly-stained with ABflo® 647 Rabbit anti-Human MMP9 mAb(A23733,5 μl/Test,orange line) or ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,blue line).Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry:1×10^6 293T(Transfection) cells were intracellularly-stained with ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,left) or ABflo® 647 Rabbit anti-Human MMP9 mAb(A23733,5 μl/Test,right). |
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