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ABflo® 647 Rabbit anti-Human TIGIT mAb (100 T)
| Reactivity: | Human |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 647. Ex:648nm. Em:664nm. |
| Gene Name: | T cell immunoreceptor with Ig and ITIM domains |
| Gene Symbol: | TIGIT |
| Synonyms: | VSIG9; VSTM3; WUCAM |
| Gene ID: | 201633 |
| UniProt ID: | Q495A1 |
| Clone ID: | 9P6V4 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-141 of human TIGIT (NP_776160.2). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-TIGIT antibody |
Background
This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.
Images
 | Flow cytometry:1×10^6 293F cells (negative control,Left) and 293F(Transfection,right) cells were surface-stained with ABflo® 647 Rabbit anti-Human TIGIT mAb(A23354,5 μl/Test,orange line) or ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry:1×10^6 293F(Transfection) cells were surface-stained with ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,left) or ABflo® 647 Rabbit anti-Human TIGIT mAb(A23354,5 μl/Test,right). |
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