Reactivity: | Human |
Applications: | FC |
Host Species: | Rabbit |
Isotype: | IgG |
Clonality: | Monoclonal Antibody |
Conjugation: | ABflo® 647. Ex:648nm. Em:664nm. |
Gene Name: | beta-2-microglobulin |
Gene Symbol: | B2M |
Synonyms: | IMD43; AMYLD6; MHC1D4 |
Gene ID: | 567 |
UniProt ID: | P61769 |
Clone ID: | 7F5Z10 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-119 of human β2 Microglobulin(NP_004039.1). |
Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
Purification Method: | Affinity purification |
Concentration: | 0.04 mg/mL |
Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
Documents: | Manual-B2M Antibody |
Background
This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.
Images
![]() | Flow cytometry: 1×10^6 Daudi cells(negative control,left) and HeLa (right) were surface-stained with ABflo® 647 Rabbit anti-Human β2 Microglobulin mAb(A24224,5 μl/Test,orange line) or ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,blue line).Non-fluorescently stained cells were used as blank control (red line). |
![]() | Flow cytometry:1×10^6 HeLa were surface-stained with ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,left) or ABflo® 647 Rabbit anti-Human β2 Microglobulin mAb(A24224,5 μl/Test,right). |
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