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ABflo® 647 Rabbit anti-Mouse CD112/Nectin-2 mAb (100 T)
| Reactivity: | Mouse |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 647. Ex:648nm. Em:664nm. |
| Gene Name: | nectin cell adhesion molecule 2 |
| Gene Symbol: | Nectin2 |
| Synonyms: | MPH; Pvr; Pvs; Cd112; Pvrl2; nectin-2 |
| Gene ID: | 19294 |
| UniProt ID: | P32507 |
| Clone ID: | 9N3R10 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 32-345 of mouse CD112/Nectin-2 (NP_033016.3). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.01 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-Nectin2 antibody |
Background
Enables cell adhesion molecule binding activity and protein homodimerization activity. Involved in homophilic cell adhesion via plasma membrane adhesion molecules. Acts upstream of or within several processes, including establishment of mitochondrion localization; sperm mitochondrion organization; and spermatid development. Located in cell-cell contact zone; plasma membrane; and zonula adherens. Is expressed in brain; cochlea; enamel organ; male reproductive system; and primitive collecting duct. Human ortholog(s) of this gene implicated in Alzheimer's disease and multiple sclerosis. Orthologous to human NECTIN2 (nectin cell adhesion molecule 2).
Images
 | Flow cytometry: 1×10^6 Raw264.7 cells (Low Expression,left) and C2C12 cells (right) were surface-stained with ABflo® 647 Rabbit anti-Mouse CD112/Nectin-2 mAb (A24091,5 μl/Test,orange line) or ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry: 1×10^6 C2C12 cells were surface-stained with ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,left) or ABflo® 647 Rabbit anti-Mouse CD112/Nectin-2 mAb (A24091,5 μl/Test,right). |
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