ABflo® 647 Rabbit anti-Mouse CD124/IL-4Ra mAb (100 T)

Brand: Abclonal
Cat. #: A24724
Availability: In Stock

$290.00

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Description

Reactivity:	Mouse
Applications:	FC
Host Species:	Rabbit
Isotype:	IgG
Clonality:	Monoclonal Antibody
Conjugation:	ABflo® 647. Ex:648nm. Em:664nm.
Gene Name:	interleukin 4 receptor, alpha
Gene Symbol:	Il4ra
Synonyms:	Il4r; CD124
Gene ID:	16190
UniProt ID:	P16382
Clone ID:	5Q6R0
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 26-233 of mouse CD124/IL-4Ra (NP_001008700.1).
Dilution:	FC,5 μl per 10^6 cells in 100 μl volume
Purification Method:	Affinity purification
Concentration:	0.04 mg/mL
Buffer:	PBS with 0.03% proclin300,0.2% BSA, pH7.3.
Storage:	Store at -20°C. Avoid freeze / thaw cycles.
Documents:	Manual-Il4ra antibody

Background

Predicted to enable cytokine receptor activity. Involved in positive regulation of chemokine production; positive regulation of cold-induced thermogenesis; and positive regulation of macrophage activation. Acts upstream of or within several processes, including defense response to protozoan; negative regulation of T-helper 1 cell differentiation; and positive regulation of immune effector process. Predicted to be located in several cellular components, including centriolar satellite; extracellular space; and nucleoplasm. Predicted to be part of receptor complex. Is expressed in several structures, including adrenal medulla; early conceptus; hemolymphoid system; medulla oblongata basal plate mantle layer; and reproductive system. Used to study asthma. Human ortholog(s) of this gene implicated in several diseases, including acne; allergic conjunctivitis; autoimmune disease (multiple); human immunodeficiency virus infectious disease; and renal tuberculosis. Orthologous to human IL4R (interleukin 4 receptor).

Images

	Flow cytometry: 1×10^6 293F cells (negative control,left) and 293F (Transfection,right) cells were surface-stained with ABflo® 647 Rabbit anti-Mouse CD124/IL-4Ra mAb (A24724,5 μl/Test,orange line) or ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line).
	Flow cytometry: 1×10^6 293F (Transfection) cells were surface-stained with ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,left) or ABflo® 647 Rabbit anti-Mouse CD124/IL-4Ra mAb (A24724,5 μl/Test,right).