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ABflo® 647 Rabbit anti-Mouse CD140b/PDGFR beta mAb (100 T)
| Reactivity: | Mouse |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 647. Ex:648nm. Em:664nm. |
| Gene Name: | platelet derived growth factor receptor, beta polypeptide |
| Gene Symbol: | Pdgfrb |
| Synonyms: | Pdgfr; CD140b; PDGFR-1 |
| Gene ID: | 18596 |
| UniProt ID: | P05622 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 32-530 of mouse CD140b/PDGFR beta (NP_032835.2). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/ml |
| Buffer: | PBS with 0.09% Sodium azide,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-Pdgfrb antibody |
Background
Enables platelet-derived growth factor-activated receptor activity and signaling receptor binding activity. Involved in several processes, including positive regulation of intracellular signal transduction; protein phosphorylation; and vasculature development. Acts upstream of or within several processes, including animal organ development; response to ceramide; and ruffle assembly. Located in cell surface; cytoplasm; and ruffle. Is expressed in several structures, including alimentary system; extraembryonic component; genitourinary system; nervous system; and sensory organ. Used to study basal ganglia calcification; infantile myofibromatosis; myeloproliferative neoplasm; and severe nonproliferative diabetic retinopathy. Human ortholog(s) of this gene implicated in basal ganglia calcification; glioblastoma; infantile myofibromatosis; myeloproliferative neoplasm (multiple); and renal cell carcinoma. Orthologous to human PDGFRB (platelet derived growth factor receptor beta).
Images
 | Flow cytometry: 1×10^6 CTLL-2 cells (negative control,left) and NIH/3T3 cells (right) were surface-stained with ABflo® 647 Rabbit anti-Mouse CD140b/PDGFR beta mAb (A26691,5 μl/Test,orange line) or ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry: 1×10^6 NIH/3T3 cells were surface-stained with ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,left) or ABflo® 647 Rabbit anti-Mouse CD140b/PDGFR beta mAb (A26691,5 μl/Test,right). |
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