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ABflo® 647 Rabbit anti-Mouse CD16 mAb (100 T)
| Reactivity: | Mouse |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 647. Ex:648nm. Em:664nm. |
| Gene Name: | Fc receptor, IgG, low affinity III |
| Gene Symbol: | Fcgr3 |
| Synonyms: | CD16 |
| Gene ID: | 14131 |
| UniProt ID: | A0A0B4J1M6 |
| Clone ID: | 2A7Y1 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 38-207 of mouse CD16(NP_034318.2). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.01 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-Fcgr3 antibody |
Background
Enables IgG binding activity and IgG receptor activity. Acts upstream of or within several processes, including antibody-dependent cellular cytotoxicity; phagocytosis; and positive regulation of hypersensitivity. Located in external side of plasma membrane. Is expressed in liver and spleen. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); dengue disease (multiple); hematologic cancer (multiple); leukopenia (multiple); and malaria (multiple). Orthologous to human FCGR2A (Fc fragment of IgG receptor IIa).
Images
 | Flow cytometry: 1×10^6 Neuro-2a cells (negative control,left) and C57BL/6 mouse Splenocytes (right) were surface-stained with ABflo® 647 Rabbit anti-Mouse CD16 mAb (A24936,5 μl/Test,orange line) or ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry: 1×10^6 C57BL/6 mouse Splenocytes were surface-stained with ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,left) or ABflo® 647 Rabbit anti-Mouse CD16 mAb (A24936,5 μl/Test,right). |
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