Reactivity: | Mouse |
Applications: | FC |
Host Species: | Rabbit |
Isotype: | IgG |
Clonality: | Monoclonal Antibody |
Conjugation: | ABflo® 647. Ex:648nm. Em:664nm. |
Gene Name: | nerve growth factor receptor (TNFR superfamily, member 16) |
Gene Symbol: | Ngfr |
Synonyms: | p75; LNGFR; p75NTR; p75NGFR; Tnfrsf16 |
Gene ID: | 18053 |
UniProt ID: | Q9Z0W1 |
Clone ID: | 9Q3T2 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 32-254 of mouse CD271 (NP_150086.2) . |
Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
Purification Method: | Affinity purification |
Concentration: | 0.04 mg/mL |
Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
Documents: | Manual-Ngfr antibody |
Background
Enables death receptor activity; nerve growth factor binding activity; and small GTPase binding activity. Involved in several processes, including cellular glucose homeostasis; circadian regulation of gene expression; and dorsal aorta development. Acts upstream of or within several processes, including hair follicle morphogenesis; nervous system development; and regulation of signal transduction. Located in several cellular components, including cell surface; cell-cell junction; and postsynaptic density. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in Alzheimer's disease and mental depression. Orthologous to human NGFR (nerve growth factor receptor).
Images
![]() | Flow cytometry:1×10^6 293F cells (negative control,Left) and 293F(Transfection) cells (Right) were surface-stained with ABflo® 647 Rabbit anti-Mouse CD271/NGFR mAb(A24322,5 μl/Test,orange line) or ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
![]() | Flow cytometry:1×10^6 293F(Transfection) cells were surface-stained with ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,left) or ABflo® 647 Rabbit anti-Mouse CD271/NGFR mAb(A24322,5 μl/Test,right). |
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