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ABflo® 647 Rabbit anti-Mouse CD366 (TIM-3) mAb (100 T)
| Reactivity: | Mouse |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 647. Ex:648nm. Em:664nm. |
| Gene Name: | hepatitis A virus cellular receptor 2 |
| Gene Symbol: | Havcr2 |
| Synonyms: | Tim3; TIM-3; Timd3 |
| Gene ID: | 171285 |
| UniProt ID: | Q8VIM0 |
| Clone ID: | 7K7P3 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-191 of mouse CD366 (TIM-3)(NP_599011.2) |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-Havcr2 antibody |
Background
Predicted to enable metal ion binding activity. Involved in several processes, including regulation of cytokine production; regulation of leukocyte activation; and toll-like receptor signaling pathway. Located in cell surface; early endosome; and immunological synapse. Is expressed in several structures, including dorsal aorta; gut; liver; lung; and reproductive system. Human ortholog(s) of this gene implicated in hepatocellular carcinoma and renal cell carcinoma. Orthologous to human HAVCR2 (hepatitis A virus cellular receptor 2).
Images
 | Flow cytometry:1×10^6 MCF7 cells (negative control,Left) and RAW 264.7 cells (Right) were surface-stained with ABflo® 647 Rabbit anti-Mouse CD366 (TIM-3) mAb (A22779,5 μl/Test,orange line) or ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry:1×10^6 RAW 264.7 cells were surface-stained with ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,left) or ABflo® 647 Rabbit anti-Mouse CD366 (TIM-3) mAb (A22779,5 μl/Test,right). |
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