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ABflo® 647 Rabbit anti-Mouse Integrin alpha 2/CD49b mAb (100 T)
| Reactivity: | Mouse |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 647. Ex:648nm. Em:664nm. |
| Gene Name: | integrin alpha 2 |
| Gene Symbol: | Itga2 |
| Synonyms: | DX5; GPIa; CD49B |
| Gene ID: | 16398 |
| UniProt ID: | Q62469 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 168-366 of mouse Integrin alpha 2/CD49b (NP_032422.2). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/ml |
| Buffer: | PBS with 0.09% Sodium azide,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-Itga2 antibody |
Background
Enables amyloid-beta binding activity. Predicted to be involved in several processes, including cell surface receptor signaling pathway; positive regulation of cell migration; and positive regulation of cellular component organization. Predicted to act upstream of or within cell adhesion. Located in basal part of cell and external side of plasma membrane. Is expressed in several structures, including alimentary system; brain; cardiovascular system; eye; and genitourinary system. Human ortholog(s) of this gene implicated in several diseases, including Behcet's disease; artery disease (multiple); blood platelet disease (multiple); diabetes mellitus (multiple); and von Willebrand's disease (multiple). Orthologous to human ITGA2 (integrin subunit alpha 2).
Images
 | Flow cytometry: 1×10^6 C57BL/6 mouse splenocytes were surface-stained with ABflo® 488 Rabbit anti-Mouse CD161c/NK1.1 mAb (A24922,5 μl/Test) and ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,left) or ABflo® 647 Rabbit anti-Mouse Integrin alpha 2/CD49b mAb (A26560,5 μl/Test,right). |
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