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ABflo® 700 Rabbit anti-Human CD119/IFNGR1 mAb (100 T)
| Reactivity: | Human |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 700. Ex:690nm. Em:713nm. |
| Gene Name: | interferon gamma receptor 1 |
| Gene Symbol: | IFNGR1 |
| Synonyms: | CD119; IFNGR; IMD27A; IMD27B |
| Gene ID: | 3459 |
| UniProt ID: | P15260 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 18-245 of human CD119/IFNGR1. (NP_000407.1). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/ml |
| Buffer: | PBS with 0.09% Sodium azide,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-IFNGR1 Antibody |
Background
This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.
Images
 | Flow cytometry: 1×10^6 Human PBMC were surface-stained with ABflo® 700 Rabbit IgG isotype control (A25976,5 μl/Test,left) or ABflo® 700 Rabbit anti-Human CD119/IFNGR1 mAb (A26745,5 μl/Test,right). |
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