Reactivity: | Human |
Applications: | FC (intra) |
Host Species: | Rabbit |
Isotype: | IgG |
Clonality: | Monoclonal Antibody |
Conjugation: | ABflo® 700. Ex:690nm. Em:713nm. |
Gene Name: | marker of proliferation Ki-67 |
Gene Symbol: | MKI67 |
Synonyms: | KIA; MIB-; MIB-1; PPP1R105 |
Gene ID: | 4288 |
UniProt ID: | P46013 |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 2271-2370 of human Ki67 (NP_002408.3). |
Dilution: | FC (intra),5 μl per 10^6 cells in 100 μl volume |
Purification Method: | Affinity purification |
Concentration: | 0.01 mg/ml |
Buffer: | PBS with 0.09% Sodium azide,0.2% BSA, pH7.3. |
Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
Documents: | Manual-MKI67 Antibody |
Background
Enables protein C-terminus binding activity. Involved in regulation of chromosome segregation and regulation of mitotic nuclear division. Located in chromosome; nuclear body; and nucleolus. Colocalizes with condensed chromosome. Implicated in Crohn's disease; breast cancer; human immunodeficiency virus infectious disease; and pancreatic cancer. Biomarker of several diseases, including Barrett's esophagus; autoimmune disease of musculoskeletal system (multiple); endocrine gland cancer (multiple); gastrointestinal system cancer (multiple); and interstitial cystitis.
Images
![]() | Flow cytometry: 1×10^6 knockout (KO) HeLa cells (negative control,left) and HeLa cells (right) were intracellularly-stained with ABflo® 700 Rabbit anti-Human Ki67 mAb (A26737,5 μl/Test,orange line) or ABflo® 700 Rabbit IgG isotype control (A25976,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
![]() | Flow cytometry: 1×10^6 HeLa cells were intracellularly-stained with ABflo® 700 Rabbit IgG isotype control (A25976,5 μl/Test,left) or ABflo® 700 Rabbit anti-Human Ki67 mAb (A26737,5 μl/Test,right). |
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