APC/Cyanine7 Rabbit anti-Human/Monkey CD127/IL-7Rα mAb (100 T)

Brand: Abclonal
Cat. #: A27437
Availability: In Stock

$328.00

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Description

Reactivity:	Human,Monkey
Applications:	FC
Host Species:	Rabbit
Isotype:	IgG
Clonality:	Monoclonal Antibody
Conjugation:	APC-Cy7. Ex:651nm. Em:779nm.
Gene Name:	interleukin 7 receptor
Gene Symbol:	IL7R
Synonyms:	ILRA; CD127; IL7RA; CDW127; IMD104; sIL-7R; lnc-IL7R; IL7Ralpha; IL-7Ralpha; IL-7R-alpha
Gene ID:	3575
UniProt ID:	P16871
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 21-236 human CD127/IL-7Rα (NP_002176.2).
Dilution:	FC,5 μl per 10^6 cells in 100 μl volume
Purification Method:	Affinity purification
Concentration:	0.04 mg/ml
Buffer:	PBS with 0.09% Sodium azide,0.2% BSA, pH7.3.
Storage:	Store at -20°C. Avoid freeze / thaw cycles.
Documents:	Manual-IL7R Antibody

Background

The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found.

Images

	Flow cytometry: 1×10^6 Human PBMC were surface-stained with PE Rabbit anti-Human CD3 mAb (A27110,5 μl/Test) and APC/Cyanine7 Rabbit IgG isotype control (5 μl/Test,left) or APC/Cyanine7 Rabbit anti-Human/Monkey CD127/IL-7Rα mAb (A27437,5 μl/Test,right). Cells in the lymphocyte gate were used for analysis.
	Flow cytometry: 1×10^6 Monkey PBMC were surface-stained with APC/Cyanine7 Rabbit IgG isotype control (5 μl/Test,left) or APC/Cyanine7 Rabbit anti-Human/Monkey CD127/IL-7Rα mAb (A27437,5 μl/Test,right). Cells in the Lymphocyte gate were used for analysis.