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| Reactivity: | Human |
| Applications: | FC |
| Host Species: | Mouse |
| Isotype: | IgM |
| Clonality: | Monoclonal Antibody |
| Conjugation: | APC. Ex:650nm. Em:660nm. |
| Gene Name: | CD1a molecule |
| Gene Symbol: | CD1A |
| Synonyms: | R4; T6; CD1; FCB6; HTA1 |
| Gene ID: | 909 |
| UniProt ID: | P06126 |
| Immunogen: | A synthesized peptide derived from human CD1a. |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.02 mg/ml |
| Buffer: | PBS with 0.09% Sodium azide,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-CD1A Antibody |
Background
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternative splicing results in multiple transcript variants.
Images
 | Flow cytometry: 1×10^6 HeLa cells (negative control,left) and MOLT-4 cells (right) were surface-stained with APC Mouse anti-Human CD1a mAb (A26904,5 μl/Test,orange line) or APC Mouse IgG isotype control (5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry: 1×10^6 MOLT-4 cells were surface-stained with APC Mouse IgG isotype control (5 μl/Test,left) or APC Mouse anti-Human CD1a mAb (A26904,5 μl/Test,right). |
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