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APC Rabbit anti-Human CD244/2B4 mAb (100 T)
| Reactivity: | Human |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | APC. Ex:650nm. Em:660nm. |
| Gene Name: | CD244 molecule |
| Gene Symbol: | CD244 |
| Synonyms: | 2B4; NAIL; Nmrk; NKR2B4; SLAMF4 |
| Gene ID: | 51744 |
| UniProt ID: | Q9BZW8 |
| Immunogen: | Recombinant Protein corresponding to a sequence within amino acids 22-221of human CD244/2B4 (NP_001160135.1). |
| Dilution: | FC, 5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/ml |
| Buffer: | PBS with 0.09% Sodium azide,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-CD244 antibody |
Background
This gene encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Images
 | Flow cytometry: 1×10^6 K-562 cells (negative control,left) and HEL cells (right) were surface-stained with APC Rabbit anti-Human CD244/2B4 mAb (A26837,5 μl/Test,orange line) or APC Rabbit IgG isotype control (A24173,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry: 1×10^6 HEL cells were surface-stained with APC Rabbit IgG isotype control (A24173,5 μl/Test,left) or APC Rabbit anti-Human CD244/2B4 mAb (A26837,5 μl/Test,right). |
 | Flow cytometry:1×10^6 Human PBMC were surface-stained with ABflo® 450 Mouse anti-Human CD56 mAb (5 μl/Test) and APC Rabbit IgG isotype control (A24173,5 μl/Test,left) or APC Rabbit anti-Human CD244/2B4 mAb (A26837,5 μl/Test,right). Cells in the lymphocyte gate were used for analysis. |
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