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APC Rabbit anti-Mouse CD162/PSGL-1 mAb (100 T)
| Reactivity: | Mouse |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | APC. Ex:650nm. Em:660nm. |
| Gene Name: | selectin, platelet (p-selectin) ligand |
| Gene Symbol: | Selplg |
| Synonyms: | CD162; Psgl1; Selp1; Selpl; Psgl-1 |
| Gene ID: | 20345 |
| UniProt ID: | Q3TA56 |
| Clone ID: | 4J2V5 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 18-320 of mouse CD162/PSGL-1 (NP_033177.3). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/ml |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-Selplg antibody |
Background
Involved in leukocyte adhesive activation. Acts upstream of or within leukocyte tethering or rolling. Predicted to be located in plasma membrane raft and uropod. Predicted to be active in plasma membrane. Is expressed in brain and thymus primordium. Human ortholog(s) of this gene implicated in carotid artery disease. Orthologous to human SELPLG (selectin P ligand).
Images
 | Flow cytometry: 1×10^6 NIH/3T3 cells (negative control,left) and C57BL/6 mouse splenocytes cells (right) were surface-stained with APC Rabbit anti-Mouse CD162/PSGL-1 mAb (A25950,5 μl/Test,orange line) or APC Rabbit IgG isotype control (A24173,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry: 1×10^6 C57BL/6 mouse splenocytes cells were surface-stained with APC Rabbit IgG isotype control (A24173,5 μl/Test,left) or APC Rabbit anti-Mouse CD162/PSGL-1 mAb (A25950,5 μl/Test,right). |
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