| Reactivity: | Mouse |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | APC. Ex:650nm. Em:660nm. |
| Gene Name: | neuropilin 1 |
| Gene Symbol: | Nrp1 |
| Synonyms: | Nrp; NP-1; Npn1; NPN-1; C530029I03 |
| Gene ID: | 18186 |
| UniProt ID: | P97333 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-856 of mouse CD304/Neuropilin-1 (NP_032763.2). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/ml |
| Buffer: | PBS with 0.09% Sodium azide,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-Nrp1 antibody |
Background
Enables protein kinase binding activity; transmembrane signaling receptor activity; and vascular endothelial growth factor binding activity. Involved in several processes, including nervous system development; regulation of signal transduction; and vasculature development. Acts upstream of or within several processes, including morphogenesis of a branching epithelium; nervous system development; and toxin transport. Located in several cellular components, including endosome; focal adhesion; and neurofilament. Is integral component of postsynaptic membrane. Is expressed in several structures, including cardiovascular system; jaw; lung; nervous system; and sensory organ. Used to study retinal vein occlusion. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human NRP1 (neuropilin 1).
Images
![]() | Flow cytometry: 1×10^6 CHO cells (negative control,left) and CHO (Transfection,right) cells were surface-stained with APC Rabbit anti-Mouse CD304/Neuropilin-1 mAb (A26587,5 μl/Test,orange line) or APC Rabbit IgG isotype control (A24173,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
![]() | Flow cytometry: 1×10^6 C57BL/6 mouse splenocytes were surface-stained with APC Rabbit IgG isotype control (A24173,5 μl/Test,left) or APC Rabbit anti-Mouse CD304/Neuropilin-1 mAb (A26587,5 μl/Test,right). |
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