Reactivity: | Mouse |
Applications: | FC |
Host Species: | Rabbit |
Isotype: | IgG |
Clonality: | Monoclonal Antibody |
Conjugation: | APC. Ex:650nm. Em:660nm. |
Gene Name: | inducible T cell co-stimulator |
Gene Symbol: | Icos |
Synonyms: | H4; CCLP; AILIM; CRP-1; Ly115 |
Gene ID: | 54167 |
UniProt ID: | Q9WVS0 |
Clone ID: | 3N5O9 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-142 of mouse ICOS/CD278(NP_059508.2). |
Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
Purification Method: | Affinity purification |
Concentration: | 0.04 mg/ml |
Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
Documents: | Manual-Icos antibody |
Background
Predicted to be involved in T cell costimulation; T cell tolerance induction; and cell-cell adhesion. Located in external side of plasma membrane. Is integral component of plasma membrane. Used to study common variable immunodeficiency. Human ortholog(s) of this gene implicated in celiac disease; common variable immunodeficiency; and immunoglobulin alpha deficiency. Orthologous to human ICOS (inducible T cell costimulator).
Images
![]() | Flow cytometry: 1×10^6 CHO cells (negative control,left) and CHO (Transfection,right) cells were surface-stained with APC Rabbit anti-Mouse ICOS/CD278 mAb (A25964,5 μl/Test,orange line) or APC Rabbit IgG isotype control (A24173,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
![]() | Flow cytometry: 1×10^6 CHO (Transfection) cells were surface-stained with APC Rabbit IgG isotype control (A24173,5 μl/Test,left) or APC Rabbit anti-Mouse ICOS/CD278 mAb (A25964,5 μl/Test,right). |
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