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| Reactivity: | Mouse |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | Unconjugated |
| Gene Name: | tumor necrosis factor receptor superfamily, member 13b |
| Gene Symbol: | Tnfrsf13b |
| Synonyms: | Taci; 1200009E08Rik |
| Gene ID: | 57916 |
| UniProt ID: | Q9ET35 |
| Clone ID: | 9M10C8 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 5-129 of mouse CD267/TACI (NP_067324.1). |
| Dilution: | FC,1:500 - 1:1000 |
| Purification Method: | Affinity purification |
| Concentration: | 1.12 mg/mL |
| Buffer: | PBS with 0.05% proclin300,0.05% BSA,50% glycerol, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-Tnfrsf13b antibody |
Background
Acts upstream of or within B cell homeostasis; hematopoietic progenitor cell differentiation; and negative regulation of B cell proliferation. Located in external side of plasma membrane. Is integral component of plasma membrane. Is expressed in renal vasculature. Used to study systemic lupus erythematosus. Human ortholog(s) of this gene implicated in common variable immunodeficiency. Orthologous to human TNFRSF13B (TNF receptor superfamily member 13B).
Images
 | Flow cytometry: 1×10^6 Neuro-2a cells (negative control,left) and A20 cells (right) were surface-stained with CD267/TACI Rabbit mAb (A24921,2 μg/mL,orange line) or ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/test,blue line), followed by Alexa Fluor® 647 conjugated goat anti-rabbit pAb staining. Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry: 1×10^6 A20 cells were surface-stained with ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/test,left) or CD267/TACI Rabbit mAb (A24921,2 μg/mL,right). |
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