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| Reactivity: | Human |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | Unconjugated |
| Gene Name: | integrin subunit beta 5 |
| Gene Symbol: | ITGB5 |
| Synonyms: | Integrin beta-5 |
| Gene ID: | 3693 |
| UniProt ID: | P18084 |
| Clone ID: | 5U9H2 |
| Immunogen: | Recombinant Protein corresponding to a sequence within amino acids 24-490 of human Integrin β5/ITGB5 (NP_002204.2). |
| Dilution: | FC,1:100 - 1:500 |
| Purification Method: | Affinity purification |
| Concentration: | 1.1 mg/mL |
| Buffer: | PBS with 0.05% proclin300,0.05% BSA,50% glycerol, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-ITGB5 Antibody |
Background
This gene encodes a beta subunit of integrin, which can combine with different alpha chains to form a variety of integrin heterodimers. Integrins are integral cell-surface receptors that participate in cell adhesion as well as cell-surface mediated signaling. The alphav beta5 integrin is involved in adhesion to vitronectin.
Images
 | Flow cytometry: 1×10^6 Jurkat cells (negative control,left) and A549 cells (right) were surface-stained with Integrin β5/ITGB5 Rabbit mAb (A24824,5 μl/Test,orange line) or ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,blue line), followed by Alexa Fluor® 647 conjugated goat anti-rabbit pAb staining. Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry: 1×10^6 A549 cells were surface-stained with ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,left) or Integrin β5/ITGB5 Rabbit mAb(A24824,5 μl/Test,right). |
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