Reactivity: | Human |
Applications: | FC |
Host Species: | Rabbit |
Isotype: | IgG |
Clonality: | Monoclonal Antibody |
Conjugation: | PE. Ex:565nm. Em:574nm. |
Gene Name: | C-X-C motif chemokine receptor 5 |
Gene Symbol: | CXCR5 |
Synonyms: | BLR1; CD185; MDR15 |
Gene ID: | 643 |
UniProt ID: | P32302 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-47aa of human CD185/CXCR5 (NP_033981.2). |
Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
Purification Method: | Affinity purification |
Concentration: | 0.02 mg/ml |
Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
Documents: | Manual-CXCR5 Antibody |
Background
This gene encodes a multi-pass membrane protein that belongs to the CXC chemokine receptor family. It is expressed in mature B-cells and Burkitt's lymphoma. This cytokine receptor binds to B-lymphocyte chemoattractant (BLC), and is involved in B-cell migration into B-cell follicles of spleen and Peyer patches. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Images
![]() | Flow cytometry: 1×10^6 HeLa cells (negative control,left) and Daudi cells (right) were surface-stained with PE Rabbit anti-Human CD185/CXCR5 mAb (A26188,5 μl/Test,orange line) or PE Rabbit IgG isotype control (A24172,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
![]() | Flow cytometry: 1×10^6 Daudi cells were surface-stained with PE Rabbit IgG isotype control (A24172,5 μl/Test,left) or PE Rabbit anti-Human CD185/CXCR5 mAb (A26188,5 μl/Test,right). |
![]() | Flow cytometry: 1×10^6 Human PBMC were surface-stained with PE Rabbit IgG isotype control (A24172,5 μl/Test,left) or PE Rabbit anti-Human CD185/CXCR5 mAb (A26188,5 μl/Test,right). |
![]() | Flow cytometry:1×10^6 Human PBMC were surface-stained with ABflo® 647 Mouse anti-Human CD19 mAb (5 μl/Test) and PE Rabbit IgG isotype control (A24172,5 μl/Test,left) or PE Rabbit anti-Human CD185/CXCR5 mAb (A26188,5 μl/Test,right). Cells in the lymphocyte gate were used for analysis. |
You may also be interested in: