PE Rabbit anti-Human CD262/DR5/TRAILR2 mAb (100 T)

Brand: Abclonal
Cat. #: A26741
Availability: In Stock

$248.00

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Description

Reactivity:	Human
Applications:	FC
Host Species:	Rabbit
Isotype:	IgG
Clonality:	Monoclonal Antibody
Conjugation:	PE. Ex:565nm. Em:574nm.
Gene Name:	TNF receptor superfamily member 10b
Gene Symbol:	TNFRSF10B
Synonyms:	DR5; CD262; KILLER; TRICK2; TRICKB; ZTNFR9; TRAILR2; TRICK2A; TRICK2B; TRAIL-R2; KILLER/DR5
Gene ID:	8795
UniProt ID:	O14763
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 56-182 of human CD262/DR5/TRAILR2 (NP_003833.4).
Dilution:	FC,5 μl per 10^6 cells in 100 μl volume
Purification Method:	Affinity purification
Concentration:	0.04 mg/ml
Buffer:	PBS with 0.09% Sodium azide,0.2% BSA, pH7.3.
Storage:	Store at -20°C. Avoid freeze / thaw cycles.
Documents:	Manual-TNFRSF10B Antibody

Background

The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.

Images

	Flow cytometry: 1×10^6 HEL cells (negative control,left) and HeLa cells (right) were surface-stained with PE Rabbit anti-Human CD262/DR5/TRAILR2 mAb (A26741,5 μl/Test,orange line) or PE Rabbit IgG isotype control (A24172,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line).
	Flow cytometry: 1×10^6 HeLa cells were surface-stained with PE Rabbit IgG isotype control (A24172,5 μl/Test,left) or PE Rabbit anti-Human CD262/DR5/TRAILR2 mAb (A26741,5 μl/Test,right).