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| Reactivity: | Human |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | PE. Ex:565nm. Em:574nm. |
| Gene Name: | integrin subunit beta 3 |
| Gene Symbol: | ITGB3 |
| Synonyms: | GT; GT2; CD61; GP3A; BDPLT2; GPIIIa; BDPLT16; BDPLT24 |
| Gene ID: | 3690 |
| UniProt ID: | P05106 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-718 of human CD61 (NP_000203.2). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/ml |
| Buffer: | PBS with 0.09% Sodium azide,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-ITGB3 Antibody |
Background
The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.
Images
 | Flow cytometry: 1×10^6 U-937 cells (negative control,left) and HEL cells (right) were surface-stained with PE Rabbit anti-Human CD61 mAb (A26518,5 μl/Test,orange line) or PE Rabbit IgG isotype control (A24172,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry: 1×10^6 HEL cells were surface-stained with PE Rabbit IgG isotype control (A24172,5 μl/Test,left) or PE Rabbit anti-Human CD61 mAb (A26518,5 μl/Test,right). |
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