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PE Rabbit anti-Human CD62L/L-Selectin mAb (100 T)
| Reactivity: | Human |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | PE. Ex:565nm. Em:574nm. |
| Gene Name: | selectin L |
| Gene Symbol: | SELL |
| Synonyms: | TQ1; LAM1; LEU8; LNHR; LSEL; CD62L; LYAM1; PLNHR; LECAM1 |
| Gene ID: | 6402 |
| UniProt ID: | P14151 |
| Clone ID: | 2Q7X7 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 39-332 of human CD62L/L-Selectin (NP_000646.3). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.02 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-SELL Antibody |
Background
This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene.
Images
 | Flow cytometry: 1×10^6 T-47D cells(negative control,left) and MOLT-4 cells (right) were surface-stained with PE Rabbit anti-Human CD62L/L-Selectin mAb(A24249,5 μl/Test,orange line) or PE Rabbit IgG isotype control (5 μl/Test,blue line).Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry: 1×10^6 T-47D cells(negative control) were surface-stained with PE Rabbit anti-Human CD62L/L-Selectin mAb(A24249,5 μl/Test,orange line) or PE Rabbit IgG isotype control (5 μl/Test,blue line).Non-fluorescently stained T-47D cells were used as blank control (red line). |
 | Flow cytometry:1×10^6 MOLT-4 cells were surface-stained with PE Rabbit IgG isotype control (5 μl/Test,left) or PE Rabbit anti-Human CD62L/L-Selectin mAb(A24249,5 μl/Test,right). |
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