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PE Rabbit anti-Human Neuropilin-2/NRP2 mAb (100 T)
| Reactivity: | Human |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | PE. Ex:565nm. Em:574nm. |
| Gene Name: | neuropilin 2 |
| Gene Symbol: | NRP2 |
| Synonyms: | NP2; NPN2; PRO2714; VEGF165R2 |
| Gene ID: | 8828 |
| UniProt ID: | O60462 |
| Clone ID: | 1P1J6 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-855 of human Neuropilin-2/NRP2 (NP_957718.1). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.01 mg/ml |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-NRP2 Antibody |
Background
This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F}, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. This protein has also been determined to act as a co-receptor for SARS-CoV-2 (which causes COVID-19) to infect host cells.
Images
 | Flow cytometry: 1×10^6 U-251 MG cells were surface-stained with PE Rabbit IgG isotype control (A24172,5 μl/Test,left) or PE Rabbit anti-Human Neuropilin-2/NRP2 mAb (A25939,5 μl/Test,right). |
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